Primary liver cancer is an extremely dangerous malignant tumor, with a high incidence rate in China, accounting for about 55% of the world total, and short natural survival period, with a course of 3~6 months, low overall 5-year survival rate, and no specific effective treatment at present. Primary liver cancer has a high degree of malignancy, and most of them are in the middle or late stage when they are clearly diagnosed, and the traditional surgery, chemotherapy or radiotherapy cannot achieve the ideal effect. Traditional Chinese medicine (TCM) has greater advantages in the treatment of intermediate and advanced primary liver cancer, and its efficacy is certain, which shows the promising prospect of TCM in the fight against cancer, and it is one of the effective therapeutic means for conquering liver cancer in multiple ways and means. However, at present, there is a lack of objective indexes for TCM identification and typing, and most of them do not have a control group, which makes the credibility of the efficacy affected to some extent. The therapeutic effect on middle and late-stage patients is still unsatisfactory. Although there are individual cured cases, there are fewer cases, and the therapeutic prescription is partial to diffusion, which is difficult to summarize and improve. Summarizing years of clinical experience, we have applied the method of strengthening the body to treat primary liver cancer, and achieved better efficacy in controlling the tumor, prolonging the survival period of the patients, and improving the quality of life of the patients. There is no disease name of “liver cancer” in Chinese medical literature, but according to its clinical manifestations, it can be attributed to the category of “dystocia, accumulation, jaundice, dropsy” and other diseases, just as the “Spiritual Pivot? Water distension,” said: “abdominal distension body are large, large and skin distension, etc., color pale yellow, abdominal tendons, this is also its symptoms.”, “difficult to understand” said: “the body is large, large and skin distension, etc., color pale yellow, abdominal tendons, this is also. The “Difficult Classic” says: “The accumulation of spleen is called Planktonia. In the stomach and epigastric region, the abdomen is as big as a disk, which does not heal for a long time. People have less than four limbs, jaundice, and diet is not for the skin.” The understanding of the etiology and pathogenesis of liver cancer is basically the same, i.e., liver cancer is a symptom of the basic deficiency and the standard reality, and the basic deficiency is the weakness of the spleen and stomach, insufficient qi and blood, and loss of positive qi, just as the “Medical Zong must read the chapter of Cumulative aggregation” said, “Cumulative accumulation of the formation of the deficiency of positive qi, and then the evil qi entrenched.” The source of all diseases and wait for the theory of accumulation of disease Hou” said: “accumulation, by the yin and yang disharmony, visceral weakness, subject to wind and evil, fighting in the visceral gas for also.” ; and the standard real that the evil within, blood stasis fire poison, such as “Suwen? Lift the pain theory” said: “Cold guest in the small intestine membrane between the original, blood, blood astringency can not be injected into the large meridian, blood gas can not be line, so the host of the past and into the carries on.” The “Danxi Xinfa” said: “All people in the body under the block is more phlegm.” The Danxi Xinfa says: “Anyone who has lumps in his body is mostly phlegm. At the beginning of the onset of liver and spleen deficiency, blood and gas stasis, over time, the gas depression and fire, dampness and heat within the resulting fire and toxicity, blood stasis and gas congestion, paralysis and obstruction, so see the accumulation of lumps, jaundice, dropsy and other symptoms. In the late stage, due to the evil venom exhaustion and blood injury, the positive qi loss, mostly see Yin deficiency and fluid loss, liver, spleen and kidney damage. Among them, “this” is the dominant role of spleen deficiency. Therefore, the treatment of this disease is based on strengthening the spleen, tonifying qi, nourishing qi and blood, nourishing the liver and kidney, and according to the different stages of the development of the disease and symptoms, supplemented with methods such as dredging the liver and regulating qi, activating blood circulation and removing blood stasis, clearing away heat and detoxifying toxins, clearing dampness and heat, softening and dispersing knots, eliminating syndromes and destroying stagnant cells, nourishing the liver and kidney, and calming the liver and quenching wind, etc, but the support of the uprightness and solidification of the essence should be put in the first place. Most of the middle and late stage liver cancer patients admitted in our clinic are physically weakened, and their positive energy is already weak and cannot withstand the damage of surgery and the side effects of chemotherapy. According to the theory of Chinese medicine, “Nei Jing” says: “When the positive qi exists inside, the evil can not be dried up, and when the evil plays, its qi will be weak”. Our clinical practice is to strengthen the spleen and regulate qi, replenish qi and blood, and nourish the liver and kidney with traditional Chinese medicines, such as Codonopsis pilosula, Atractylodes macrocephala, Astragalus membranaceus, Zihechuan, Radix Rehmanniae Praeparata, Rhizoma Dioscoreae, Rhizoma Dioscoreae, Rhizoma Dioscoreae, Rhizoma Dioscoreae, Rhizoma Dioscoreae, and so on. 1.Combined with mental depression, chest and rib lumps, abdominal distension and liver pain, bitter mouth and poor appetite, red and blue tongue, stringy pulse are damp-heat stagnation, and are often combined with Herba Inulae, Poria cocos, Dandelion, Gentian herb, Snake Tongue Herb, Sempervirens, Hedyotis diffusa, Pseudostellaria, Plantago asiatica, Poria, and so on, in order to clear away heat, relieve dampness and remove toxins and eliminate stagnation. Heat-clearing and detoxifying herbs have antibacterial and anti-inflammatory, antiviral and anti-tumor effects, and are one of the common treatments for various cancer patients. Some patients with cold stomach may have hidden pain and discomfort in the stomach after taking the medicine, and the pain can be relieved if it is changed to be taken after meals. 2. “Long-term diseases will have blood stasis”, advanced liver cancer often has blood stasis, manifesting as dark color, abdominal distension like a drum, enlarged liver and spleen, dark red tongue, varicose veins on the back of tongue, petechiae and ecchymosis on the side of tongue, and fine stringy pulse, which belongs to stagnation of qi and blood stasis, and the microcirculation of the nail folds manifests that the tube tripping loops are twisted and thickened, and the cohesion of blood cells is in a state of muddy flow. The medication should be equipped with common drugs such as Chai Hu, Bai Shao, Mu Xiang, Fo Huan, Chuan Pu, Chuan Neem Zi, Red Peony, Safflower, Peach Kernel, Salvia Miltiorrhiza, Yujin, Trigonelline, Curcuma longa, Bupleurum and other commonly used medicines in order to invigorate blood circulation and remove blood stasis and regulate qi stagnation. However, it should be used cautiously for patients with hepatocellular carcinoma who have hemorrhage or subcutaneous hemorrhage in case of triggering gastrointestinal bleeding. 3.If the patient has fatigue and weakness, tastelessness, abdominal distension and poor appetite, ascites and edema, pale and fat tongue with white greasy moss, slippery or weak pulse, he/she has spleen deficiency and dampness obstruction. Often with Poria, Shenquan, raw Job’s tears, sand nuts, Chenpi, half-summer, psyllium, zedoary, wood, etc. in order to harmonize the stomach to eliminate stagnation, dispel dampness and phlegm. 4, if the manifestation of fatigue and laziness, low fever and heartburn, insomnia and dreaminess, red tongue with little moss, weak pulse is a deficiency of yin in the liver and kidney. It is suitable to use Radix Salviae Praeparata, Ophiopogon, Radix Rehmanniae Praeparata, Fructus Bupleurum, Fritillariae Cirrhosae, Radix Paeoniae Alba, Radix et Rhizoma Dampaeaeae, Radix et Rhizoma Puerariae, Fructus Lycii, etc., in order to benefit the qi and nourish the yin and to nourish the water. Since the tumor is a local manifestation of systemic disease, it is necessary to adjust the internal organs from a holistic point of view, support the correctness and solidify the root, activate the meridians and activate the collaterals, and soften the hardness and dissipate the knots, in order to improve the clinical efficacy. Typical case: Li Mou, female, 54 years old, on March 12, 2004, consulted the doctor. Complaint: right epigastric distension and discomfort, progressive wasting for 3 months. History: In early 2004, the patient had right upper abdominal distension and discomfort, which was aggravated after eating, and progressive wasting. 6×7cm space-occupying lesion in the right lobe of the liver near the hepatoportal area was detected by ultrasound and CT examination in a local hospital in Taiwan, and the patient was found to have AFP2030ug/ml, ALT453U/L, ASL422U/L, and TBIL32.8umol/LDBIL15umol/L. The diagnosis was primary hepatocellular carcinoma. primary liver cancer. Because of the difficulty and high risk of surgery, the patient turned to a Chinese medicine practitioner for consultation. At the first consultation, the patient complained of distension and discomfort in the right upper abdomen, which was aggravated after eating, dullness, dry mouth, yellow drowning, knotty stools, red tongue with thin yellow coating and stringy pulse, physical examination: body was emaciated, face was slightly yellow, there was no liver palms and spider nevus, superficial lymph nodes were not enlarged, abdominal softness, the liver was 3cm below the ribs of the right midline of the clavicle, and not yet reached under the rapier protuberance, and the spleen was not large. The treatment should strengthen the spleen and regulate qi, dredge the liver and disperse the stagnation, clear heat and diuresis. Prescription: Radix Codonopsis pilosulae 15g, Rhizoma Atractylodis Macrocephalae 12g, Rhizoma Atractylodis Macrocephalae 15, Rhizoma Lentinus 15, Radix et Rhizoma Aspergillus 20g, Job’s tears 30, Pericarpium Citri Reticulatae 6g, Rhizoma Inulae 15g, Poria cocos 30g, Radix et Rhizoma Dandelionatae 15g, Rhizoma Ulmoides 12g, Rhizoma Serpentis Macrocephalae 15g, Radix et Rhizoma Bidentatae 12g, Radix Paeoniae Alba 15g. Second diagnosis: after a month of re-visit, the right epigastric distension is reduced, no aggravation after eating, the Na is still OK, the drowning is a little yellow, the stool is normal, the tongue is red, the moss is thin and yellow, the pulse is thin and stringy, the body weight is increased by 2 kilograms, the dampness and heat are removed by seven points, the liver is stagnant and the junctions are relieved. Prescription: Codonopsis 15g, Atractylodes macrocephala 12g, Zihechemia 15, Job’s tears 30, Pericarpium Citri Reticulatae 6g, Phellodendron Bidentatae 15g, Poria cocos 30g, Yujin 12g, Cortex Eucommiae 15g, Radix Achyranthis Bidentatae 12g, Radix et Rhizoma Gastrodiae 20g, Radix Paeoniae Alba 15g. Third diagnosis: the distension of the right epigastric region basically disappeared, Na Shangke, urine and feces are normal, the face is reddish and moist, body weight is gained, the tongue is pale red, moss thinly yellow and the pulse is fine. The effect does not change the formula, still abide by the preceding plus and minus treatment. Sixth diagnosis: the patient was re-examined in November 2004 in the local hospital in Taiwan, the lesion in the right lobe of the liver near the hilar area was reduced to 3×4cm, AFP was reduced to 406.18ug/ml, ALT65U/L, ASL57U/L, TBIL8umol/LDBIL5umol/L. Now there was no distension and stuffiness of the right epigastric region, the patient’s appetite and urination were normal, his complexion was red and his body weight increased to 62kg, his tongue was pale red with thin coating. 62 kilograms, tongue pale red with thin yellow moss, pulse stringy. The patient’s general condition is good, and he is living like a normal person. He continues to take traditional Chinese medicine treatment, together with dietary and spiritual conditioning. Experience Middle and advanced liver cancer often lost the chance of treatment such as surgical resection, hepatic artery chemoembolization, etc. The treatment of TCM, TCM intervention, liver protection and systemic supportive therapy became the main treatment means. Among them, traditional Chinese medicine treatment of middle and advanced liver cancer has the advantages of significant improvement of symptoms, small side effects, better maintenance of systemic status, slower development of disease, shrinkage of tumor or long-term survival with tumor, etc. Moreover, it can make the patient’s AFP decrease and liver function obviously improve, thus traditional Chinese medicine occupies an important position in the comprehensive treatment of middle and advanced liver cancer. Some scholars used spleen-healthy and qi regulating traditional Chinese medicine together with external radiation can make the 5-year survival rate of middle- and advanced-stage hepatocellular carcinoma reach 43%. Experimental research on spleen-healthy and qi regulating traditional Chinese medicine in Cancer Hospital of Shanghai Medical University has proved that: it can regulate the immune function and inhibit the growth of tumors, it has the effect of delaying and treating the pre-cancerous lesions in liver induced by diethylnitrosamine and the hepatic tumors induced by ethylstilbestrol, it can decrease the level of serum AFB1-albumin The experimental results proved that the effect of spleen-strengthening and qi regulating traditional Chinese medicine on tumor cells is mainly inhibition rather than direct killing, and the spleen-strengthening and qi regulating formula is mainly a tonic medicine, not mainly attacking and destroying. This is also one of the reasons why the side effects of the traditional Chinese medicine for strengthening the spleen and regulating qi are small. Experimental research also shows that Chinese medicine for strengthening the spleen and regulating qi has the effect of promoting apoptosis of tumor cells and inhibiting the proliferation of tumor cells. Chinese medicine can be used as an adjuvant therapy to participate in the whole process of tumor treatment. According to the different symptoms and signs of patients and the etiology and pathogenesis at different stages of the disease, it can be used to identify and classify the symptoms and types of tumors, and then make legislative prescriptions to carry out targeted treatment, which is a widely used method nowadays. It is characterized by maintaining the characteristics of the holistic concept theory of Chinese medicine, embodying the completeness of reasoning, method, prescription and medicine, and giving full play to the specialties of Chinese medicine’s diagnosis and treatment. As for advanced tumors, the palliative treatment of TCM is mainly used to strengthen the body, enhance immunity, inhibit tumor, strengthen the spleen and regulate qi, increase the appetite, strengthen the body, nourish yin and stomach, improve the patient’s quality of life and prolong the survival period. However, poisonous drugs or raw herbs against cancer should be used with caution, because poisonous drugs have toxicity, impairing liver and kidney functions, especially for advanced tumors; while raw herbs have complex composition, cannot be purified, and contain very little active ingredients, with poor efficacy. Secret prescription for cancer treatment is a modern superstition, harmful to people, and even more undesirable. Fuzheng is based on the overall concept of Chinese medicine, the concept of the unity of heaven and earth and mankind, and the concept of the balance of yin and yang. In fact, it is not purely the application of tonic and strong medicines, but it should regulate the balance of yin and yang, qi and blood, internal organs, meridians and collaterals of the human body as well as the method of enhancing the ability of the organism to fight against cancer, and thus, the Chinese medicine’s “tonic, adjustment, and, benefit” are all part of the Fuzheng. Therefore, “tonifying, adjusting, harmonizing and benefiting” of Chinese medicine belongs to the category of corrective measures. Through clinical and experimental researches, it has been proved that the method of supporting justice and consolidating fundamentals has multiple effects, which are summarized as follows: it can improve the clinical symptoms of patients with tumors, improve the effects of surgery, radiotherapy and chemotherapy, and prolong the survival period; reduce the toxic and side effects of radiotherapy and chemotherapy, and improve the body’s anticancer function, including the immune function; reduce the chances of metastasis and recurrence in patients with tumors; and improve the quality of life of patients. In conclusion, patients with middle and late-stage liver cancer can be treated mainly with the method of supporting and consolidating the root of liver cancer, which can control the growth of tumor, improve the quality of life of patients and prolong the survival period.