I. Types of primary liver cancer? 1. Massive type; 2. Nodular type; 3. Diffuse type; 4. Microscopic hepatocellular carcinoma <2cm; small hepatocellular carcinoma <5cm; 5. Large hepatocellular carcinoma >5cm; giant hepatocellular carcinoma >10cm. 2. Causes of primary liver cancer? Various types of hepatitis (hepatitis B up to 90%); 2. Cirrhosis; 3. Dietary carcinogens (e.g. aflatoxin, etc.); 4. Hereditary factors; 5. Chronic inflammation, stones and parasites. III. Diagnosis of primary liver cancer? 1. Pathologic diagnosis (most accurate); 2. Clinical diagnosis (according to medical history, physical signs, AFP examination, etc.); 3. Imaging diagnosis (ultrasound, CT, MRI, hepatic arteriography, etc.). Clinical manifestations of primary liver cancer? 1. Pain in liver area; 2. Digestive symptoms (loss of appetite, abdominal distension, nausea and vomiting, diarrhea, etc.); 3. Weakness, emaciation; 4. Fever; 5. Accompanying cancer manifestations: hypoglycemia, erythrocytosis; hypercalcemia, hypercholesterolemia, etc.). V. Serum AFP test for primary liver cancer? AFP ≥400ng/ml; 2. Exclude chronic hepatitis, liver cirrhosis, testicular or ovarian embryonal tumor, pregnancy at the same time; 3. 30% of hepatocellular carcinoma have normal AFP. Imaging examination of primary liver cancer? Ultrasound: it can show the tumor, size, shape, location, portal vein thrombus, etc., with a diagnostic compliance rate of about 90%; 2. CT: with a diagnostic compliance rate of about 90%, it can determine whether the tumor can be resected or not, the relationship between the tumor and the blood vessels, and the measurement of the volume of the liver; 3. MRI: to differentiate between benign and malignant tumors, and to reconstruct the imaging of the liver blood vessels and bile ducts; 4. Hepatic arteriography. Differential diagnosis of primary liver cancer? 1, Metastatic hepatocellular carcinoma; 2, Cirrhotic nodules; 3, Benign liver tumors (e.g. hepatic hemangioma, hepatic adenoma, etc.); 4, Tumors of adjacent organs (stomach, pancreas, gallbladder, kidney or adrenal gland). VIII. Complications of primary liver cancer? 1, rupture and bleeding of liver cancer; 2, upper gastrointestinal bleeding; 3, liver failure; 4, bloody ascites; 5, metastatic manifestations of liver cancer: such as neurological symptoms of brain metastasis, lumbar and leg pain of bone metastasis. Treatment of primary liver cancer? 1. Hepatic resection (radical or palliative resection); 2. Interventional hepatic artery embolization chemotherapy; 3. Radiofrequency or microwave therapy for hepatocellular carcinoma; 4. Liver transplantation; 5. Chemotherapy or radiotherapy; 6. Immunotherapy and gene therapy; 7. Traditional Chinese medicine treatment. What are the indications for surgical resection of liver cancer? 1. Good general condition, able to tolerate surgery; 2. No obvious jaundice, ascites or extensive metastasis; 3. No coagulation dysfunction; 4. Good hepatic function compensation; 5. General lesions are limited to half of the liver; 6. No invasion of the hepatic portal area or portal vein.