In general, the skin is often flushed, burning, mildly tingling, or small blisters, or in a few cases, large blisters, after the application of the medication. Most of the patient’s skin will remain pigmented for a period of time. This is a normal phenomenon, because the three volt patch itself is to use pungent and hot stimulating drugs to achieve the effect of warming and helping Yang Qi. It should be noted that on the day of the patch no cold and spicy food, three days avoid eating shrimp, crab, beef, goose and duck, peanuts, taro and egg food, patch parts should not be in cold water within ten hours, also can not use soap and other irritating items scrubbing, can be warm water bath. About the treatment of skin reactions at the patch: small blisters, generally do not need special treatment, let it absorb naturally, or give moist burn cream to reduce discomfort. Large blisters should be treated in a medical institution by picking the bottom of the blister with a sterile needle, draining the fluid and sterilizing it to prevent infection. A broken blister should be disinfected and then dressed with sterile gauze to prevent infection. In case of erythema, blistering and itching of the skin of a larger extent and to a greater degree, symptomatic treatment should be carried out immediately. Those with systemic skin allergy symptoms should be treated promptly at a hospital.