With the application of iodized salt and the development of detection technology, more and more patients with thyroid nodules are found clinically, some of them are very worried about it, fearing that it may be cancer or develop into cancer in the future. Small cancers can be completely asymptomatic and many of them are diagnosed only after metastases appear; large cancers can be diagnosed before metastases appear, so the following cases should be taken seriously: 1) those with family history, i.e. parents, siblings, uncles or aunts have thyroid cancer; 2) those with history of head or neck reflex diagnosis and treatment; 3) those with irregular shaped thyroid nodules and rapid enlargement, i.e. those that increase in size within 1 month or a few months; 4) those with thyroid nodules that increase in size within 1 month or a few months. (If the nodule increases rapidly within a few days, it is definitely not malignant, but may be inflammation or bleeding), and the treatment with thyroxine is not effective; 4. “7. The chance of malignancy is higher in single nodules than in multiple nodules, and young men who have recently developed single nodules should be more alert; 8.