Many patients with hyperthyroidism develop ocular symptoms, which we call thyroid-related ophthalmopathy, and is one of the more common diseases in ophthalmology, with the highest incidence of orbital disease. Its clinical manifestations are complex and varied, including: eyelid recession, ocular congestion, protrusion of the eyeball, late fall of the upper lid, gaze, exposure keratitis, ocular motility disorders, diplopia, optic neuropathy, etc. It causes serious damage to the patient’s visual function and appearance and is quite tricky to treat. Almost all patients have eye discomfort symptoms, such as eye redness, foreign body sensation, dryness, photophobia, tearing, visual fatigue, eye pain, etc., which obviously affect daily life and work. Below I will briefly introduce the specific causes of this problem. 1. Current research shows that thyroid-related eye disease is an autoimmune disease that leads to eye inflammation, resulting in swollen eyelids, conjunctival congestion and edema (increased redness and blood in the whites of the eyes), photophobia, and foreign body sensation. 2. Thyroid-related eye disease can lead to inflammatory damage to the lacrimal gland, affecting the tear secretion function and leading to dry eyes, foreign body sensation, and fatigue. 3. When thyroid-related eye disease involves the eyelids or protruding eyeballs, it is possible to develop impingement. The contact with the cornea and conjunctiva not only causes damage and pain, but also irritates the eye and causes tearing. 4. Thyroid-related eye disease presents with receding and delayed eyelid drop, increased eye exposure, and accelerated tear production, resulting in dry eyes, foreign body sensation, and photophobia. 5. Thyroid-related ophthalmopathy leads to changes in the relationship between the eyelid and the eye, uneven tear distribution, changes in tear flow, and ocular discomfort. 6. Thyroid-related ophthalmopathy involves the extraocular muscles, causing eye movement disorders and even diplopia, which can add to the symptoms of fatigue. 7. When thyroid-related ophthalmopathy appears with incomplete eye closure, conjunctival and corneal epithelial defects and exposure keratitis may occur, resulting in severe eye discomfort symptoms and even threatening the eye and vision.