Winter and spring, climate change, in daily life people, especially the elderly and children often encounter fever, headache, vomiting and other situations, often some people with their so-called experience, simply go to the pharmacy to buy some of their own such as cold medicine fee, antipyretic drugs to eat, even to the hospital, may only go to the general clinic or small hospital for general antibacterial class and antiviral treatment. There is no visit to a hospital with neurological specialties. These fever, headache and other conditions after antibacterial class and antiviral treatment if not relieved, the condition continues to worsen, and even convulsions, mental disorders, etc., should be alert to meningitis, commonly tuberculous meningitis, viral encephalitis. In recent years, the incidence of viral and tuberculosis diseases is on the rise worldwide, and the number of patients with tuberculous meningitis in particular has also increased significantly. The disease can occur in infants, children, adolescents and adults. In the early stages, the disease often presents only with fever and headache, without typical symptoms of TB toxicity such as afternoon fever, night sweats, and fatigue, and the cranial C-T scan is mostly normal, so it is easy to miss or misdiagnose. With the development of the disease, when the diagnosis is confirmed by high fever, coma and limb paralysis, the treatment effect is often unsatisfactory and the sequelae are easily left behind. Therefore, when treatment for fever and headache is ineffective, it is necessary to go to a tuberculosis clinic for examination and, if necessary, lumbar puncture for cerebrospinal fluid testing, so that tuberculous meningitis can be diagnosed early, treated early, and completely cured, leaving no residual problems.