There is no theoretical basis to confirm that vitamin C should not be taken at night. In general, vitamin C can usually be taken in moderation at night. When there are symptoms of vitamin C deficiency or inadequate dietary intake, vitamin C supplementation is required and there is no specific time requirement. However, care needs to be taken to avoid long-term or overdose, if long-term large amounts of oral vitamin C may cause increased stomach acid, gastric reflux, nausea, vomiting, abdominal pain, diarrhea and other adverse reactions, and can lead to higher uric acid in the blood, increasing the risk of kidney stones and other diseases. In addition, if a large amount of vitamin C is taken for a long time and then suddenly stopped, symptoms of vitamin C deficiency may also occur. Since vitamin C is an acidic substance, it should not be taken on an empty stomach, otherwise it will lead to excessive secretion of stomach acid, which will easily cause nausea and other uncomfortable symptoms. Vitamin C is derived from fresh fruits and vegetables, and the daily intake of sufficient fruits and vegetables can meet the daily needs of the body. If the intake or absorption of vitamin C is insufficient or the consumption is excessive, additional supplementation is required according to medical advice.