Recently, our orthopedic spine surgery group has completed several cases of advanced and difficult minimally invasive percutaneous vertebroplasty (PVP) and posteromedial kyphoplasty (PKP), relieving the pain of these patients who came to us with osteoporotic compression fractures of the spine due to unbearable pain. Patients with osteoporotic compression fractures of the spine may have a clear history of a fall, a history of exertion such as lifting heavy objects or even quilts, or even no clear history of trauma, making many fractures susceptible to underdiagnosis or misdiagnosis. Previously, we had several patients with pain that was still more pronounced 4 months after the injury and MRI showed that the fracture was still fresh and that the fracture was more significantly compressed (even compressed into pieces) than when it was first detected. In several cases, the patients had pain in the thoracic back and were seen in the emergency room with coronary artery disease, which was excluded after relevant examinations. A chest radiograph revealed a fracture of the upper thoracic spine, which was considered to be a pain caused by the fracture and intercostal nerve irritation, and the pain symptoms were relieved after surgery. Conservative treatment of compression fractures of the spine in elderly patients is mostly bed rest and pain medication, which is long and ineffective, and may cause kyphosis, which may shift the center of weight, increase the risk of falls and injuries, reduce lung capacity and heart function, and aggravate existing medical diseases. In a few patients, conservative treatment is ineffective and open surgery is required, but the results are poor due to factors such as loosening of internal fixation. Percutaneous vertebroplasty (PVP) is a new technique that uses minimally invasive techniques to inject biomaterials such as bone cement into the vertebral body via the skin and the pedicle under the supervision of image-enhancing equipment to restore the height of the vertebral body, prevent further collapse and deformity of the vertebral body, reduce pain and improve function. It is used to treat vertebral hemangiomas, vertebral metastases, myeloma and osteoporotic vertebral compression fractures. Percutaneous kyphoplasty (PKP) involves placing an expandable balloon catheter into the vertebral body, injecting a contrast medium under pressure to expand the balloon, repositioning the fractured vertebral body and creating a safe space, releasing the contrast medium, withdrawing the balloon, and injecting bone cement under low pressure. PKP can correct kyphosis, reduce postoperative pain and inject bone cement at low pressure, which can reduce cement leakage. Currently, the cost of PVP and PKP surgical instruments is 10-40,000 RMB, and the procedure is still a fully self-pay procedure that cannot be reimbursed by most hospitals. In our department, the operation is performed under local anesthesia, which requires little physical condition of the patient, less blows, less trauma, 15-30 minutes of operation time, only one puncture needle eye on the skin, no suture, fracture pain can disappear when turning over after the operation, no infusion after the operation, able to go down on the same day, and can be discharged the next day. By performing this type of surgery and combining it with stepwise treatment of osteoporosis (medication, percutaneous minimally invasive surgery, and open orthopedic surgery), patients with spinal compression fractures are relieved of their symptoms, avoiding the discomfort and complications associated with long-term bed rest, improving their quality of life, and reducing the incidence of posterior convexity deformity associated with fractures, benefiting a large number of patients with osteoporosis.