There are several clinical methods to determine the benignity and malignancy of thyroid nodules: a. The nature of thyroid nodules can be assessed by ultrasound examination of the thyroid gland. If ultrasound examination reveals that there are obvious blood flow signals around the thyroid nodules, obvious calcification foci within the nodules, the aspect ratio of the nodules is greater than one, the border is unclear, the shape is irregular, and the texture is uneven, the possibility of malignancy of the nodules is high and it is recommended that Patients are recommended to undergo surgery. If the nodule does not have the characteristics of malignant tumor mentioned above, with small volume, clear border and uniform echogenicity, it is mostly suggestive of benign lesion. Malignant nodules can be seen under ultrasonography with contrast shadows surrounding the nodules, while benign nodules have no contrast filling around them due to the absence of obvious blood flow signals. Third, fine-needle aspiration of the nodule by ultrasound guidance and smear pathology is the only way to accurately determine the nature of the thyroid nodule.