The discomfort caused by prostate puncture biopsy consists of two parts:
- One is the discomfort caused by placing the ultrasound probe and puncture gun into the rectum, which is similar to that during a rectal exam and mostly tolerable;
- Second, the discomfort caused by the puncture needle passing through the rectal wall into the prostate.
Because the puncture needle is thin and the entry is rapid and instantaneous, it produces less pain and is generally tolerable when the patient is calm and relaxed. A small number of patients still feel localized pain after the puncture, which can be treated with oral analgesics.
In general, most hospitals perform transrectal prostate puncture with local mucosal surface anesthesia and transperineal puncture with local infiltration anesthesia.