1.What is HPV?
Answer.
HPV means human papillomavirus, a DNA virus, spherical, 45 to 55 nm in diameter, symmetrical 20-sided body without envelope, with 72 shell grains; human is its only host, host cells are skin and mucosal epithelium; it is sensitive to disinfectants, tolerant to freezing and drying, and generally survives in glycerol at -20°C for at least
2 to 5 months, and usually enters the exposed basal cells in wounds by direct contact.
2.What is high-risk HPV and what types does it include?
A: HPV is classified into low-risk types (such as HPV-6/-11) and high-risk types (HPV-16/-18) according to whether the lesions have malignant potential; HPV-16/-18 is closely related to cervical cancer.
3.What are the common skin diseases caused by HPV?
A: common warts, flat warts, plantar warts, condyloma acuminata.
4, common warts have what clinical manifestations?
A: Common warts are commonly known as “wart”, “wart”. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things.
6, what is condyloma acuminata? What are the modes of transmission?
A: Condyloma acuminatum is the genital, perineal and anal area epidermolysis bullosa; its transmission channels include sexual contact, auto-inoculation, mother-to-child transmission, contaminant transmission; single sexual contact transmission rate of 25%;
7, the clinical manifestations of condyloma acuminata?
A: The incubation period of condyloma acuminata 3 weeks – 8 months, an average of 3 months; infection is divided into three cases: ① clinical infection (visible damage to the naked eye), ② subclinical infection (no damage to the naked eye, white acetate test to see or histology has typical changes
) ③ latent infection (HPV within normal looking skin mucosa without morphological changes), the majority of which are latent or subclinical infections. Initially, they are light red papules, which gradually increase in size and form papule-like, papillate, cauliflower-like or cockle-shaped growths. It occurs on the skin mucosa near the external genitalia and anus, such as the glans prepuce, coronal groove, urethral opening, perianal area, and ties in men; the labia, clitoris, cervix, vaginal opening, vagina, and perineum in women; and a few occur outside the anogenital area (e.g., oral cavity, axilla, breast, and interdigital toe). Most people do not have any clinical symptoms, a few have itching, burning pain, increased leucorrhea.
8, condyloma acuminata why easy to recur?
A: HPV infection of the skin mucosa, the incubation period is long, the infection is divided into three cases, both clinical infection, subclinical infection, latent infection. The majority of these are latent or subclinical infections, the latter two being the main cause of recurrence. The actual fact is that there is no way to eradicate HPV infection, oral antiviral drugs are basically ineffective, and the 3-month recurrence rate of various therapies is >25%.
9, the current condyloma acuminata treatment methods are what?
A: Chemical methods: 0.5% onychotoxin, 5% 5-Fu cream, 50-90% trichloroacetic acid solution;
Physical/surgical methods: liquid nitrogen freezing, CO2 laser, electrocautery, microwave, surgery; immunotherapy: 5% Imiquimod, interferon; photochemotherapy: photodynamic.
10.What is photodynamic therapy?
A: It is a photochemical reaction caused by light energy excitation photosensitizer, which can be used to selectively destroy biological tissues; its principle is that the cells at the lesion intake photosensitizer, under the action of a specific light source reaction, the production of oxygen radicals, monomorphic oxygen and other substances, thereby damaging the cell membrane and vascular endothelial cells, selectively kill the lesion cells and achieve therapeutic purposes. The actual fact that it is possible to treat subclinical and latent infection lesions, thus greatly reducing the recurrence rate of condyloma acuminata.
11.What is risky sexual behavior?
A: It means having unprotected sex (such as vaginal intercourse, anal intercourse, oral intercourse, breast intercourse) with high-risk people (such as sex workers, drug addicts, sexually promiscuous people).