Klippel-Trenaunay syndrome, a congenital peripheral vascular disorder, was first reported by French physicians Klippel and Trenaunay in 1900 and was named “varicose veins with hypertrophic vascular nevus of bone”. In addition, there are many other names: Klippel-Trenaunay-Weber syndrome, Weber’s syndrome, Ollierklippel’s syndrome, Trenaunay’s syndrome, Parkes-Weber’s syndrome, vascular bone hypertrophy syndrome, bone hypertrophic capillary hemangioma syndrome, hypertrophic warty nevus, hypertrophic Vascular dilatation, etc., is mainly a manifestation of congenital abnormal vascular development. Treatment There is no special treatment method yet, but mainly symptomatic reduction of symptoms. If the limb length difference exceeds 1.9 cm, the heel of the healthy side can be padded to prevent secondary lesions caused by long-term limping. For the thickening of the affected limb, medical elastic stockings or elastic bandages should be used for compression therapy, which can control varicose veins, reduce the heaviness and swelling of the lower limbs caused by venous stasis, and prevent the occurrence of thrombotic superficial phlebitis. For the superficial varicose veins with normal function of deep veins and valves, local varicose shallow injection of sclerotherapy or laser treatment can be performed. However, this method is not applicable to patients with deep venous defects. In children with arteriovenous fistulas or bilateral limbs of unequal length, bilateral arteriograms of the lower limbs can be performed first, and if abnormal vessels are found, they can be embolized, but the effect is short-lived, and the non-dominant fistula will “wake up” and open up; even open surgery, i.e., “dead branch therapy”, is used to achieve However, this is a large investment with low results, and there is a risk of muscle ulceration and necrosis of the limb. The treatment needs to be cautious. For children with cavernous hemangioma, hemangioma sclerotherapy is feasible.