Wash your face with water to remove the mixture of oil, dander and bacteria from the surface of your skin. However, do not over-wash. Do not squeeze or scratch the acne. In addition, avoid using oil and grease, powder skin care cosmetic products and ointments and creams containing glucocorticoid ingredients. Topical medication 1. Vitamin A acid drugs: ①0,025%~0,1% Vitamin A acid (all-trans Vitamin A acid) cream or gel: This drug can regulate the differentiation of epidermal keratin-forming cells, so that acne dissolves and is discharged. The skin is slightly irritated at the beginning of 5~12 days, such as local flushing, flaking, tightness or burning sensation, but it can gradually disappear. Therefore, it should be used from low concentration and applied once a night to avoid increasing drug irritation after light exposure, and topical application once a week after symptoms improve. ②13-cis-retinoic acid gel: regulate the differentiation of epidermal keratin-forming cells and reduce sebum secretion, once or twice a day. ③2nd generation retinoids: 0, 1% adapalene gel, 1 time per night, good efficacy for mild and moderate acne. 0, 1% tazarotene cream or gel, 1 time every other night to reduce local irritation. 2 . Benzoyl peroxide: This drug is a peroxide, which can slowly release neo-oxygen and benzoic acid after topical application, with the effect of killing Propionibacterium acnes, dissolving acne and astringency. It can be formulated into 2, 5%, 5% and 10% different concentrations of lotions, emulsions or gels, and should be used from a low concentration. Gel containing 5% benzoyl peroxide and 3% erythromycin can improve the efficacy. 3, antibiotics: erythromycin, chloramphenicol or clindamycin (clindamycin) prepared with ethanol or propylene glycol, the concentration of 1% to 2%, more effective. 1% clindamycin phosphate solution does not contain oil and ethanol water-soluble lotion, suitable for dry and sensitive skin acne patients. 1% clindamycin solution is also effective. 4, azelaic acid: This drug can reduce the skin surface, hair follicles and sebaceous glands in the flora, especially on Propionibacterium acnes has an inhibitory effect and acne lysis effect, for different types of acne are effective. It is effective for different types of acne. It can be formulated as a 15%-20% cream for external use, and its adverse effects are local erythema and tingling. 5, selenium disulfide: 2, 5% selenium disulfide lotion has the effect of inhibiting fungi, parasites and bacteria, and can reduce the free fatty acid content of the skin. Use for clean skin, with a slightly diluted solution evenly coated in the seborrhea obvious parts, about 20min and then wash with water. 6. Sulfur lotion: 5%~10% sulfur lotion has the function of regulating the differentiation of keratin-forming cells and reducing the free fatty acid of the skin, and also has a certain inhibitory effect on Propionibacterium acnes.