Patients with kidney disease take hormones because they have anti-inflammatory and anti-immune effects. If it is acute interstitial nephritis, a small amount of oral hormone is needed to relieve it after 3-5 days. If the patient is nephrotic syndrome, especially microscopic lesion type, membranous nephropathy, etc., hormone therapy needs to be applied, which is using its anti-immune principle. Because some types of nephrotic syndrome are immune system diseases, if not actively treated, the inflammatory mediators and immune system will react and eventually lead to renal insufficiency or even renal failure, so the application of hormones to anti-immune therapy can play a role in controlling the disease progression and even the possibility of curing the disease. Hormone is one kind of anti-immunotherapy, and some patients with ineffective hormone can also choose other immunosuppressive drugs, such as tacrolimus and cyclosporine.