[Abstract] OBJECTIVE: To standardize the preliminary screening method of X-ray small intestine barium meal examination for small intestine diseases, in order to improve its clinical application value, reduce the examination procedure, and lower the X-ray radiation dose to patients. METHODS: One hundred and fifty-two cases of X-ray small bowel barium meal examination for gastrointestinal diseases without history of gastrointestinal surgery and congenital anomalies were collected and divided into three groups according to Rome III criteria: normal group, functional group and instrumental group, and the time of barium reaching the ileocecal region was recorded by the same method. One-way ANOVA was used to analyze the variability of the time of barium reaching the ileocecal region by simple abdominal pain, blood in stool, bloating, diarrhea and other symptoms (including tumor). RESULTS: The time of barium reaching the ileus in the normal, instrumental and functional groups was (214.91±93.64), (210.14±121.89) and (63.52±29.63) minutes, respectively, and the time of barium reaching the ileus in the normal and instrumental groups was longer than that in the functional group (P<0.05), while the time of barium reaching the ileus between the normal and instrumental groups was not There was no statistical difference between the normal group and the instrumental group (P>0.05). The time to reach the ileocecal region of the contrast medium was (85.20±85.06) minutes in cases with diarrhea as the main symptom, which was shorter than cases with simple abdominal pain, blood in stool, abdominal distention and other symptoms (including tumor) (all P<0.05). 48.68% (74/152) of patients benefited less from unnecessary X-ray radiation; barium x-ray examination helped the rest of the cases diagnosis. Conclusion: Functional intestinal diseases have the shortest time for barium to reach the ileocecal region, and barium meal angiography of the small intestine helps in the diagnosis of this disease, reduces unnecessary procedures and decreases X-ray radiation.