Based on the National Key Clinical Specialty Program, the Department of Neurosurgery of Xiangya Hospital has introduced the world’s most advanced BrainLab neuronavigation system and Southeast Asia’s first Buzz Digital Surgery Room, and has successfully carried out surgical treatments. The system can utilize CT and MRI imaging data to achieve “precise guidance – efficiently striking the target”, thus marking that the Neurosurgery Department of Xiangya Hospital has successfully stepped into the era of precise navigation. Li Xuejun, Department of Neurosurgery, Xiangya Hospital, Central South University In the past six months, using the navigation system, the diagnosis and treatment of tumors in the skull base, brainstem, thalamus, and deep brain parenchyma have achieved ideal results. Such as cavernous hemangioma and other small lesions located in the deep intracranial area, with the help of neuronavigation, it can be accurately located, with a straight incision and a small bone window, little damage to the brain tissues, and fast postoperative recovery. For intracranial gliomas, especially deep and functional lesions, with the help of preoperative imaging data (MRI, DTI, BOLD, CT, etc.), and with the help of neuronavigation and intraoperative electrophysiological monitoring, it is possible to achieve the maximum range of safe tumor resection and preserve the patient’s quality of life. For meningiomas located in the ventricles of the brain, under neuronavigation, we chose to resect the tumor through a straight incision with a small bone flap, and chose the corresponding sulcus approach, which achieved good results. In transsphenoidal surgery and extended transsphenoidal surgery, navigation can help determine the bony landmarks and key structures such as the internal carotid artery, so that the lesions can be safely and effectively resected. With the accumulation of experience, we believe that neuronavigation technology will benefit more and more patients.