Modern medicine is with the development of modern natural science and technology, computer technology, laser technology, digital automatic control of mechanical engineering and materials science and the rapid development of mutual cross-promotion, resulting in a clinical medicine, especially plastic reconstruction repair and reconstruction of surgery with practical value of the new technology – rapid prototyping technology, also known as Rapid prototyping technology (Rapid prototyping manufacture , RPM), is an emerging technology developed over the past decade, is under the control of the computer, according to the object’s computer design model or CT raw data, through the material of the precise layer, the manufacture of the prototype entity is exactly the same as the structure of the model or the physical object of the digital molding technology. Its basic principle is: the CT or MR tissue structure three-dimensional body data converted into rapid prototyping machine general STL format input RP machine, rapid prototyping machine according to the three-dimensional body data information instructions, automatically using layered manufacturing, layer by layer superimposed on the production method, rapid and direct manufacture of any complex shape of the model or physical object. Yang Bin, Maxillofacial Plastic Surgery Center, Plastic and Reconstructive Surgery Hospital, Chinese Academy of Medical Sciences Currently, rapid prototyping technology has been gradually applied to the medical field, its short production cycle, can be manufactured remotely through the Internet advantages are doubly popular. The production of craniofacial bone deformity model for plastic surgery simulation, expected transplantation of bone volume; for craniomaxillofacial bone, artificial bone joints, prosthetic limbs, such as individualized production. The success of biocompatible materials in making implantable prostheses with complex shapes and precise sizes by RP technology has inspired us to apply RP technology to explore the biomimetic fabrication of bioactive bone by rapid prototyping. Currently, Prof. Yang Bin applies rapid prototyping technology to create a craniofacial bone model of a patient with craniomaxillofacial trauma, and uses the inverse method to obtain a prosthetic model that is exactly the same as the morphology and size of the bone defect, or directly creates a biomaterial prosthesis that is in the same state as the actual one, and then uses it in the prosthetic reconstruction of craniomaxillofacial bone defects, obtaining a restorative effect that has a good morphology and function. The application and promotion of this new technology can make many patients with skull, orbital, zygomatic and maxillomandibular trauma and fracture deformity, as well as craniomaxillofacial bone defects after tumor resection obtain satisfactory treatment. Typical cases treated by Prof. Yang Bin are as follows: For details of computer-aided design CAD, computer-aided fabrication CAM, and rapid prototyping for repair and reconstruction of craniofacial, orbital, and maxillofacial bone defects, please refer to Prof. Yang Bin’s articles in Chinese Journal of Plastic and Reconstructive Surgery, 2001; Chinese Journal of Medical Aesthetics and Cosmetic Surgery, 2003; and Chinese Journal of Aesthetic Medicine, 2007.