Diabetes mellitus is a very common clinical chronic disease, with nearly 40 million in China, of which 1/4 to 1/3 will develop diabetic nephropathy, manifested as proteinuria, swelling, hypertension and renal function impairment, which is one of the main causes of uremia and dialysis and a serious threat to human health. Therefore, the prevention and treatment of diabetic nephropathy is a very important medical and social issue. Once the disease progresses to the stage of massive proteinuria, it is exceptionally difficult to treat, and modern medicine has no effective method for this, Chinese medicine has explored a lot about this, with the following characteristics. 1, pay attention to prevention, emphasizing the three early Chinese medicine is called “the upper work to cure the disease”, the treatment of the disease reflects the idea of prevention, that is, before the emergence of disease, improve the physical quality, enhance the ability to prevent disease, reduce and control its occurrence. For patients with diabetes mellitus, it is important to control blood sugar and pay attention to the presence of kidney, heart and fundus complications, and take treatment measures once they are detected. For the stage of microalbuminuria, even if it does not meet the diagnostic criteria of early diabetic nephropathy, we should start to take into account that appropriate measures taken at this stage can make the enlarged kidneys recover and the rate of urinary protein excretion can be reduced or even restored to normal. In order to cure the disease, we need “three early”, that is, early detection: early detection of diabetes or abnormal glucose tolerance, which requires annual physical examination; early diagnosis: self-perception of abnormalities and abnormal laboratory tests should be clearly diagnosed by a specialist as soon as possible; early treatment: intervention measures should be taken as soon as the diagnosis is clear, either with drugs, or diet control, exercise, or a combination of Combination of these measures. If we pay attention to prevention and early treatment, we can greatly reduce the number of cases of diabetes or diabetic nephropathy developing into uremia and dialysis. For the treatment of diabetic nephropathy, we emphasize the principles of early, long-term, comprehensive and individualized treatment. The goals of treatment are to control hyperglycemia, correct metabolic disorders, eliminate diabetic symptoms, prevent or delay complications, maintain good health and work capacity, protect children’s growth and development, prolong life expectancy, and reduce morbidity and mortality. According to the clinical manifestations, TCM emphasizes the differentiation and treatment, and the common types of symptoms include Yin deficiency and heat, Qi and Yin deficiency, Yin and Yang deficiency, and Dampness and stagnation. The application of Chinese herbal medicine can help lower blood sugar; reduce self-conscious symptoms, such as weakness, back pain, palpitation, insomnia, tinnitus, cold limbs, stubborn diarrhea, constipation, etc.; Chinese herbal enema can reduce serum creatinine and other toxins. 3.Segmental prevention and treatment, characteristic medication Our recently completed city science and technology project research concluded that the use of phased standardized treatment for diabetic nephropathy can further improve the efficacy. In the early stage (i.e., microalbuminuria stage), we use Chinese medicine to benefit qi and nourish yin + kidney tablets (or nephritis rehabilitation tablets) + basic treatment; in the middle stage (clinical stage, large amount of proteinuria or stage with renal decompensation), we use Chinese medicine to benefit qi and nourish yin, to promote dampness and eliminate stasis + nephritis spirit (or Leigongteng preparation) + basic treatment; in the late stage (renal failure stage), we use Chinese medicine to benefit qi and nourish yin, to harmonize the ligaments, to drain turbidity and detoxify toxins + kidney tablets + Chinese medicine reserved enema + basic treatment. The basic treatment includes the management of diet, blood sugar and blood pressure. Among them, Jian Kidney Tablets and Kidney Preservation Tablets are in-hospital preparations that have been used in our hospital for more than 20 years, and can also be combined with Keflex tablets for oral administration if damp-heat is obvious. The results show that the use of phased standardized treatment is more effective than various previous treatments, with more obvious effect of lowering protein, and can better delay the progress of renal function. 4, self-monitoring, lifelong care Diabetic nephropathy once it occurs is accompanied by lifelong, so far, there is no special treatment can make diabetic nephropathy eradication. Therefore, diabetic nephropathy patients should not believe in those “ancestral secret recipes, cure the root” propaganda advertising and recklessly cast a doctor. As long as you have a comprehensive understanding of the basic knowledge of diabetic nephropathy, and adhere to long-term effective treatment and self-care, prevention of major complications of diabetes and delay its development, you can prolong your life with the disease and enjoy the same quality of life and life expectancy as normal people. Therefore, it is not terrible that diabetic nephropathy cannot be cured, what is terrible is that the patient knows nothing about diabetic nephropathy and lacks the persistence to insist on long-term treatment, so that the high blood sugar status does not drop for a long time, which finally leads to various serious complications that endanger health and threaten life.