Seriously swollen, the following diseases are mainly considered: 1. Cardiac insufficiency. Most commonly seen in patients with heart failure, due to the reduction of the heart’s ejection capacity, eventually causing right heart failure resulting in stasis of blood in the body circulation, thus causing generalized edema. In this case, under the premise of treating the underlying disease, diuretics are mainly applied to improve the symptoms. Commonly used drugs, such as torasemide, spironolactone, furosemide, etc. 2, hypoalbuminemia, most commonly in patients with reduced liver function, resulting in reduced synthesis of albumin, and nephrotic syndrome, resulting in a large amount of albumin loss from the body, this condition are prone to hypoalbuminemia, so that the water in the blood vessels run into the tissue interstices causing edema. Treatment of the underlying disease and supplementation of albumin when necessary can help reduce edema. 3. Thyroid disease. For example, hypothyroidism, resulting in a decrease in the body’s secretion of thyroid hormone, is prone to generalized mucinous edema, treatment of the primary disease when necessary, supplementation of thyroxine can help improve the symptoms, commonly used drugs are levothyroxine sodium tablets.