Adult acne over the age of 25 is called late-onset acne. The main reasons for the occurrence of late-onset acne are as follows: 1. Genetic factors: Some patients with a family history of familial acne tend to have a consistently longer age of onset, so adult acne after the age of 25 is often family-related; 2. Excessive sebaceous gland secretion: The prolonged duration of acne onset may be related to facial oil secretion. The duration of acne is prolonged in people with a high secretion of sebaceous glands, so oil control is crucial in the treatment process; 3, excessive keratinization of the sebaceous ducts of the hair follicles: Especially in women with acne, it is often related to their use of poor skin care products and makeup that block the pores; 4, excessive life stress, late nights and irregular life are also causes of the aggravation of delayed acne. Because bad habits can break the balance of hormones, leading to acne. This type of acne is similar to the performance of acne during puberty, such as adult acne that occurs in women, often aggravated around puberty. Usually in the clinic, doctors will use estrogen-like drugs to give supplemental treatment to regulate and balance the hormone levels in the body. Adult acne caused by improper use of skin care products will improve significantly with daily attention to cleanliness and topical application of adapalene.