Most liver cancer patients discover the existence of their disease at an advanced stage, usually because liver cancer is insidious and not easy to be detected. So, what are the symptoms of advanced liver cancer patients? 1. Gastrointestinal symptoms: This symptom often accompanies the whole course of liver cancer patients, and usually presents various symptoms such as indigestion, appetite loss, nausea, sickness and abdominal distension, which can be easily mistaken for chronic enteritis, so we should conduct liver cancer examination in real time to prevent misdiagnosis. 2.Lethargy and weakness: Symptoms of late stage liver cancer include lethargy and weakness, which can be caused by miscellaneous digestive functions and stagnation of nutrient absorption, resulting in energy non-payment and cachexia in severe cases, affecting health; lower limb edema is also one of the late symptoms of liver cancer. Malignant cavity effusion: malignant cavity effusion is an important and malignant tumor disease. Symptoms of late stage hepatocellular carcinoma malignant cavity effusion, if not handled properly, will lead to rapid deterioration and death, so patients should pay attention to regular liver cancer examination to avoid such situation. 4. Thoracic metastasis: late stage liver cancer symptoms will include thoracic metastasis, which is more common on the right side and may include pleural effusion. Meanwhile, along with this liver cancer symptom, there are also skeletal or spinal metastases, which may have local pressure pain or nerve compression symptoms, and intracranial metastases may have neural localization signs. All these metastatic symptoms will show corresponding symptoms in the late stage of liver cancer. 5.Respiratory disorder: respiratory difficulty in advanced liver cancer symptoms is often caused by lung metastasis, and serious respiratory difficulty is easy to cause fear and sudden death if not treated in time. 6.Liver coma: Among the advanced symptoms of liver cancer, people are most unwilling to see the symptom of liver coma. During the treatment of liver cancer, there will be gastrointestinal bleeding, secondary infection, large amount of diuretics and electrolyte imbalance, which will often cause the liver coma, so special attention should be paid in liver cancer.