Ultrasonic interventional local ablation for liver cancer has become one of the three major techniques for radical treatment of liver cancer, together with surgical resection and liver transplantation, together with radio-interventional hepatic artery embolization, radiotherapy, chemotherapy, immunization and drugs as palliative, so that there is a more complete and effective method for liver cancer treatment. Our philosophy is minimally invasive, and our strategy is to use minimally invasive local treatment and mobilize the participation of human immune mechanism, not to advocate the highly invasive and highly toxic treatment measures of killing 800 enemies and damaging 1000 oneself. 1) Ultrasonic interventional microwave ablation of tumor to make it completely coagulated and necrotic, for small hepatocellular carcinoma, to play a radical role of complete local inactivation; 2) For large hepatocellular carcinoma, multiple carcinomas and important sites, the residual area after ablation is supplemented by anhydrous alcohol injection; 3) Then the growth of intrahepatic metastases is reduced or inhibited by super-selective chemotherapeutic drug injection in the portal vein of liver; 4) Strengthening nutritional support therapy, immune 4) strengthen nutritional support therapy, mobilize the body’s immunity by perihepatic injection of immunomodulators to control the growth of cancer cells, etc. The principle is to inactivate small hepatocellular carcinoma once in situ and strive to achieve radical treatment. For large hepatocellular carcinoma, we should shrink the tumor as much as possible, reduce or control the growth of the cancer, try to maintain human life and improve the quality of life. 5) Review the logistics of operation, and actively treat small cancer tumors when found. 6)Ultrasonography can visually reflect the distribution status of microvessels of hepatocellular carcinoma and the scope of tumor after ablation, which is our main evaluation means before and after surgery. Case of large hepatocellular carcinoma treatment: patient, female, 60 years old, no history of hepatitis, right hepatic mass 7x6x4.5cm, biopsy as hepatocellular carcinoma, picture 1 is intraoperative, picture 2 is preoperative ultrasound imaging, pictures 3 and 4 are the imaging evaluation after ultrasound interventional microwave ablation treatment.