The incidence of prostate cancer is very high in Europe and the United States, while it is relatively rare in China. With the development of the economic level, changes in the Chinese diet and certain lifestyle habits, the current trend of prostate cancer patients in China is increasing year by year. Unfortunately, most of the prostate cancers diagnosed in Yunnan are advanced tumors that have metastasized. What is the reason for this? 1. Prostate cancer has no specific symptoms in the early stage of its development, so patients cannot detect the abnormality at an early stage, and by the time they feel the abnormality, the tumor has already metastasized. 2. Early prostate cancer cannot be diagnosed by imaging examinations such as B-ultrasound, CT, MRI or even the more advanced PET-CT. Therefore, routine physical examination cannot detect early prostate cancer. 3. Yunnan is relatively economically and culturally backward, and most people lack proper understanding of prostate cancer, so they do not take the initiative to go to the hospital for screening of prostate cancer by urology specialists. In addition, screening for prostate cancer is not scheduled in the routine physical examination programs of various units in Yunnan Province, so the diagnosis of early prostate cancer is often delayed. It is for these reasons that patients are usually unable to diagnose prostate cancer at an early stage. So how should prostate cancer be detected early? It is actually very simple. The 2012 European Urology Guidelines and the US NCCN Guidelines both unanimously recommend the following diagnostic methods: 1. Prostate rectal examination, in which the doctor touches the texture of the prostate gland from the patient’s anus with his or her finger, is an easy way for experienced doctors to detect prostate cancer. The PSA test is to take the patient’s venous blood for laboratory test. The PSA of tumor patients is usually much higher than normal, which indicates the possibility of prostate cancer. 3.Prostate puncture biopsy, for patients who have abnormalities in the above preliminary examinations and suspect prostate cancer, prostate puncture biopsy should be performed and the specimen should be sent to the pathology department for diagnosis. This is the most accurate way to diagnose prostate cancer. In short, rectal examination and blood PSA test are preliminary screening and cannot confirm the diagnosis. Prostate puncture is required when prostate cancer is suspected in the initial screening, and only through puncture can prostate cancer be finally diagnosed. It is important to note that prostate puncture biopsy is a very specialized technical task and inexperienced non-specialist punctures often lead to missed diagnoses and increased patient suffering. A proper prostate puncture must be performed under B-ultrasound guidance for precise puncture so as to improve the accuracy of the puncture.