The blackheads and worm mites can cause certain effects on human skin, but there are obvious differences between the two in terms of clinical performance, location and nature.1. Different performance: blackheads are usually manifested as black spots in the pores of the skin surface that are significantly enlarged, extruded and shaped like worms with black tips, which are in fact oxidized lipid plugs at the tips. The face of the worm mite infection can be manifested as a red papule, with the nose as the central point of diffusion. In addition, worm mites can cause itching, redness and swelling of the patient’s skin, while blackheads generally do not feel abnormal; 2, different locations: blackheads are found on the face, forehead and back, especially more blackheads on the nose. The worm mite is mainly parasitic in human facial sebaceous glands and can be distributed all over the face, mainly around the nose and the nasal area; 3, different nature: blackheads, also known as blackhead pimples, are due to genetic factors, excessive oil secretion during puberty, resulting in excessive oil secretion by the sebaceous glands, which accumulates in the hair follicles to form lipid plugs, and are not infectious. The worm mite is a parasite that feeds on sebum in the facial skin and can secrete excrement when parasitized, which can cause inflammation of hair follicles in susceptible people and can be spread through direct or indirect contact.