The chance of kidney stones transforming into uremia is very low, generally occurring in less than 1% clinically, because uremia is a bilateral loss of physiological function of the kidneys. If it is caused by kidney stones, it must be a bilateral obstruction of the urinary system caused by bilateral kidney stones, and prolonged obstruction induces hydronephrosis leading to renal failure, or prolonged repeated stimulation of kidney stones causes urinary system infection, which leads to inflammation of the kidneys, and prolonged inflammation repeatedly stimulates the formation of chronic stimulation will lead to chronic renal insufficiency, and eventually the kidneys lose function and lead to uremia. Therefore, for those who have kidney stones, they must have bilateral kidney stones causing obstruction or infection, and a period of repeated chronic stimulation will result in bilateral kidney loss of function and uremia. Generally, the chance of this is very low, but for unilateral kidney function loss of physiological capacity is still relatively common, once found stones should be treated in a timely manner to prevent the progression of the disease to damage the kidney function.