Conception is about timing Hepatitis B couples can conceive healthy babies just like normal couples, there is no problem. It is important for hepatitis B couples to take advantage of the best time to conceive. No matter which of the couple has hepatitis B, when deciding to have a baby, they should try to ensure the following two things: one is negative for hepatitis B DNA and the other is normal liver function. If one of these two things is not met, it is not considered the best time to have a baby. Especially for women with hepatitis B, if they get pregnant when their liver function is not normal, it may not only affect the fetus, but also have a very negative impact on their own health, and some mothers-to-be have even lost their lives because of this. This is because pregnancy increases the burden on the body, and when the liver is not functioning well, it may not be able to meet the needs of the body’s metabolism and cannot bear such a heavy burden. Therefore, if a hepatitis B couple is planning to have a baby, they should see a specialist at a regular hospital before conceiving and undergo the appropriate tests. If only one partner has hepatitis B, the other partner should also get the hepatitis B vaccine in time. In comparison, men with hepatitis B are much less likely to infect the next generation, while women with hepatitis B are at greater risk of transmission to the next generation. Whether either spouse has hepatitis B, it is important to take appropriate mother-to-child interruption measures during pregnancy and after the birth of the baby. There are two main types of interruption during pregnancy: the first is for the mother-to-be to receive hepatitis B immunoglobulin injections after the fourth month of pregnancy and, if financially possible, once a month thereafter until the baby is born. Although the need for this measure is controversial, there is certainly no harm in getting the injection and it is definitely better than not getting it at all. The second method is to use medication for prevention. After the third month of pregnancy, nucleoside analogues such as lamivudine can be used. Although these drugs are not approved for use in pregnant women, there have been many publications in the literature that give positive results and safety. Professor He has also had several patients who have taken such measures and had healthy babies. However, this type of blockade has strict selection criteria, that is: it is necessary for the condition, i.e., the condition cannot be controlled without the medication; or the pregnant woman knowingly and autonomously requests or is willing to use it. Blockade is most critical after the baby is born. Babies born to hepatitis B parents should be given hepatitis B immune globulin and hepatitis B vaccine within 12 hours of birth. Both should not be injected at the same site, preferably one shot on the left and right buttocks. When the baby is 1 month old and 6 months old, another hepatitis B vaccination will be given respectively. If no antibodies are produced after the full vaccination, you can double the dose and give the vaccination again. If antibodies are still not produced, no further vaccination is necessary. More than 90% of the above blocking measures are effective. In addition to the above-mentioned blocking measures during pregnancy and after delivery, parents with hepatitis B need to take some protective measures when feeding their babies. If the mother has hepatitis B and is hepatitis B DNA negative and has normal liver function, and has breast milk to feed, she should first express her milk and do DNA and hepatitis B two-to-one test, if both are negative, then she can express her milk into a bottle and bottle feed her baby. The main reason for doing this is to prevent the baby from biting through the mother’s nipple and causing infection. Hepatitis B mothers with positive hepatitis B DNA and abnormal liver function are better off not breastfeeding. Parents or other members of the family should also take other protective measures for the baby, including: not kissing the baby mouth-to-mouth; not sharing towels, toothpaste, utensils and other items; and not feeding the baby food from their own mouths. However, general contact, like hugging, touching, and kissing on the face, will not lead to transmission.