Thyroid disorders may be associated with discomfort at the base of the tongue and it is advisable to consult a doctor. Patients with subacute thyroiditis may have symptoms of upper respiratory tract infections such as sore throat, muscle aches, fever, etc. for a period of time prior to the onset of the disease, which may cause discomfort in the base of the tongue. Thyroid nodules that are large enough to cause pressure may cause pressure on the throat, resulting in a similar discomfort at the base of the tongue. In addition, eating foods that are too hot or too cold, such as ice cream, cold drinks, hot pots, and food allergies, may also cause tongue discomfort, but not necessarily due to thyroid disease. It is advisable to consult a doctor if necessary.