Azithromycin can be used in the treatment of mycoplasma infectious diseases. Mycoplasma is the smallest microorganism that lives outside the cell, a prokaryotic cell type microorganism that lacks a cell wall, which is different from bacteria and different from viruses. Mycoplasma does not have a cell wall, and penicillins or cephalosporins, antibacterial drugs, are less effective in treating mycoplasma infections. Azithromycin belongs to macrolide antibiotics, and mycoplasma and chlamydia, etc., are relatively sensitive to macrolide antibiotics, so azithromycin is suitable for mycoplasma and chlamydia infections, and can get better treatment effect. Azithromycin can be used clinically to treat a series of infectious diseases caused by mycoplasma and chlamydia infections, such as upper respiratory tract infections, lower respiratory tract infections, acute otitis media, tonsillitis, and urinary tract infections. The macrolide antibiotics commonly used for mycoplasma infections, in addition to azithromycin, include erythromycin, roxithromycin, and clarithromycin, all of which have anti-microbial infection effects. Azithromycin in the treatment of mycoplasma infection, need to pay attention to the length of medication, it is recommended to strictly under the guidance of doctors, timely observation of secretions or other clinical symptoms, according to the condition of timely adjustment of the dose of drugs. Usually, after the symptoms of mycoplasma-induced infectious diseases disappear, do not rush to stop the medication, but need to perform mycoplasma testing again until the mycoplasma completely turns negative to confirm the cure of the disease. In addition, pay attention to whether the patient has an allergic reaction to azithromycin, and if allergy is found, stop the drug immediately and seek medical attention. During the medication period, pay attention to a light diet, quit smoking and alcohol, and avoid spicy and stimulating foods. Pay attention to rest in daily life and avoid overexertion due to strenuous exercise, etc.