Mycoplasma is the smallest known organism that can live freely and the smallest prokaryotic cell. The symptoms of mycoplasma uu positive many patients do not understand, after finding out this disease, a piece of doubt. Mycoplasma uu-positive infection is a sexually transmitted disease, mainly through sexual intercourse, but also can be indirectly transmitted by contact with the patient’s contaminated clothing. Mycoplasma uu positive symptoms are increased leucorrhea, burning urethra or cause pelvic inflammatory disease, tubal inflammatory disease and cause infertility, miscarriage and ectopic pregnancy: 1, if pregnant, because Mycoplasma solani is a conditional pathogenic bacteria, there is no definite evidence that it causes premature birth or intrauterine infection, there is no norm that must be treated during pregnancy, can wait for the postpartum review and then decide whether treatment is needed. 2. If the infertility patient is positive for mycoplasma culture or has a history of miscarriage, this situation requires treatment, and it is best to do a drug sensitivity test and then decide on the drug treatment. 3. If the patient is an ordinary patient, only UU positive, usually no symptoms, no complaints, then no treatment is needed.