The four diseases that need to be alerted to the numbness of the little toe are as follows: First, alert to cerebrovascular diseases, cerebrovascular diseases lead to symptoms of neurological deficits, manifesting as numbness of the limbs, and patients mostly have risk factors for atherosclerosis, which can be diagnosed after CT or MRI of the head; Second, alert to lumbar disc diseases, clinically more common is lumbar disc herniation or lumbar spinal stenosis, patients due to nerve compression The patient has numbness in the legs or feet and little finger due to nerve compression, which can be diagnosed after CT or MRI of the lumbar disc; Third, be alert to peripheral neuropathy, due to exposure to toxic substances in the little toe, diabetes and heavy alcohol consumption patients, peripheral nerve damage, manifested as numbness in the little toe; Fourth, numbness in the little toe is clinically seen in some of the local nerves around the little toe caused by compression, the patient is accompanied by local pain, if necessary, need to Consult orthopedics if necessary.