Adapalene gel is mainly used for the treatment of closed acne, folliculitis, and periorbicular keratosis in acne. Therefore, the onset of action varies from disease to disease and from site to site, and the onset of action is usually about 1 week to 1 month.
Adapalene gel has a certain effect on reducing the formation of microcomedema. For facial lesions, the effect is usually faster, about 1 week. However, for lesions on the back and extremities, it takes about 1 month to see significant results. Adapalene gel is irritating and photosensitive, so it is recommended to be applied topically at bedtime. Also, the use of this medication often needs to be combined with a moisturizer. Patients using this product after moisturizer application can reduce the local irritation reaction, especially for facial treatment, which can increase skin hydration, promote drug absorption, shorten the onset of action time, and can reduce the drug’s irritation reaction to the skin.
In daily life, attention should be paid to avoid spicy and irritating food, proper exercise and regular rest.