How the combination of glioma should be treated

  Gliomas are tumors that occur in the neuroectoderm and originate from neurointerstitial cells, including glial, ventricular canal, choroid plexus epithelium and neuroparenchymal cells, or neurons, collectively known as gliomas, or gliomas for short. The whole treatment of glioma should include early surgical resection and postoperative radiotherapy and chemotherapy. Since the tumor is infiltrating and there is no obvious boundary between the tumor and the brain tissue, it is difficult to completely remove the tumor, so postoperative radiotherapy and chemotherapy are necessary.  1.Surgical treatment: The principle is to remove the tumor as much as possible while preserving the neurological function. If the tumor involves two lobes but not the basal ganglia, thalamus and the opposite side, hemispheric resection can be done; if the tumor occurs in the brainstem, hypothalamus and other important nuclei, if the intracranial pressure is increased, drainage surgery can be done; if the condition is critical, it can be done first. If the tumor occurs in brainstem, thalamus and other important nuclei, if there is intracranial pressure increase, drainage surgery can be done.  2.Radiotherapy: radiotherapy should be carried out after glioma surgery. Postoperative radiotherapy can be divided into general radiotherapy or gamma knife treatment.  Chemotherapy: Highly lipid-soluble drugs that can cross the blood-brain barrier are suitable for glioma chemotherapy. Such as Temozolomide, Diqing, etc. 4.Immunotherapy: Theoretically, it is to mobilize the body’s defense ability to stop tumor growth.  5.Other: some drugs can be used to inhibit tumor growth and reduce brain edema, which can reduce clinical symptoms; those with epilepsy should apply anti-epileptic drugs before, during and after surgery.