Patients with liver cancer in their families do not necessarily inherit it because liver cancer is a malignant tumor of the digestive tract, not a hereditary disease. Most of the main causative factors of liver cancer are alcoholic liver or infection with hepatitis B and C eventually leading to cirrhosis, which is more likely to be complicated by liver cancer. Patients with family history of liver cancer must have regular review and should avoid frequent contact with patients with hepatitis B and cirrhosis, and prevent the occurrence of hepatitis B and C to reduce the occurrence of liver cancer. Patients with family history of liver cancer should also have regular medical checkups 1-2 times a year, which can effectively detect liver cancer at an early stage, enable early diagnosis and early treatment, and increase the cure rate of liver cancer patients. One should also have certain knowledge of prevention, not to be overly afraid, and to do regular medical checkups frequently, which is necessary for liver diseases, especially including liver cancer.