Pearl rash is generally referred to as pearly penile papules, which is not a sexually transmitted disease, and is considered to be related to physiological developmental variations, local irritation and other factors. Pearly penile papules are mainly skin diseases occurring on the coronal edge of the penis and the coronal sulcus, and do not belong to sexually transmitted diseases. The etiology of the disease is not clear, it may be a variation of physiological development and related to local irritation. At the same time, the disease mainly occurs in young adults aged 20 to 40 years old, and for patients with poor personal hygiene and masturbation and other bad habits, the risk of disease is relatively high. However, most of the patients have no conscious symptoms, only in the coronal groove or the coronal edge of the penis pearly papules, mostly translucent, the color can be white, light red or yellow, the growth is relatively slow. It is recommended that patients with pearly penile papules pay more attention to personal hygiene, and if necessary, consult a doctor for a clear diagnosis.