Cf252 neutron knife treatment advantages: 1. High cure rate and low recurrence rate The neutron rays emitted from Cf-252 source are high LET (energy transfer line density) rays, with high relative biological effect (RBE) and low oxygen enhanced effect ratio (OER), which can directly kill DNA molecules in tumor cells, with high DNA double-strand breakage ratio, thus its killing ability is 4-5 times stronger than conventional rays, and tumor cells rarely have sublethal loss repair after irradiation. Cancer cells rarely have sub-lethal loss repair after irradiation, so it can still achieve better treatment effect for tumors with poor radiosensitivity as well as middle and late stage and recurrent tumors. 2.Safe, non-invasive and painless treatment Neutron knife treatment does not require any incision, bleeding or general anesthesia, and the patient is completely awake during the whole treatment process, so the treatment is safe, less painful and has less impact on the patient’s health, and patients who are old, weak or cannot bear the surgery can also tolerate neutron knife treatment in general. Neutron knife treatment only takes 30 minutes to 1 hour each time. The treatment adopts the internal irradiation method, the neutron source reaches the lesion through the natural cavity of human body and irradiates the tumor tissue directly, the outward penetration distance is limited and the damage to the healthy tissue outside the tumor is extremely small; internal irradiation radiation therapy does not have the damage to the healthy tissue on the path like external irradiation, so the treatment has no side effects. Internal irradiation radiation therapy does not cause damage to healthy tissues as external irradiation does, thus the side effects and complications after treatment are mild. Because neutron knife treatment is a non-surgical treatment, patients can still retain the structure and function of their original organs after treatment, such as rectal cancer patients can retain their anus without fistula diversion, uterine cancer patients can still retain their uterus and vagina, etc.