Surgical excision of the lesion is the main treatment method. If the lesion is confined to the foreskin, circumcision can be performed, but the recurrence rate can reach about half. If the tumor invades the head of penis, partial penile excision can also be performed, which is generally sufficient at 2 cm from the tumor, and there is no tumor in the end freezing examination at the time of excision. For penile cancer without clinically touched inguinal enlargement, routine inguinal lymph node dissection is not recommended at present, because more than half of the patients may not have metastatic lesions, and skin necrosis, infection, pulmonary embolism and lymphedema of lower limbs caused by dissection surgery are quite common, which brings unnecessary pain to patients. If there are clinically suspected metastases (i.e. enlarged lymph nodes, biopsies can be taken, serial sections can be performed if necessary, and lymphatic debridement can be performed if there are metastases. Routine simultaneous lymph node dissection on both sides is generally not advocated.