Penile cancer metastasis with groin rotting indicates that the condition is more serious, which is mainly treated by radiotherapy, surgery and symptomatic treatment. 1. Radiation therapy: due to the existence of metastatic lesions, radiation therapy can be carried out to treat the metastatic foci accordingly, which can play the role of killing cancer cells as well as relieving pain. 2. Surgery: if the patient can tolerate surgery, surgery can be considered, such as lymph node surgery, through which tumor tissues and metastatic lymph nodes can be removed. For patients with lymph node metastasis, lymph node dissection can be carried out, and at the same time, trauma can be cleared, and infected and necrotic tissues can be removed. 3. Symptomatic treatment: for patients with obvious pain, pain relieving drugs can be taken under the guidance of doctor. Patients with serious localized infection and necrosis also need anti-infection treatment. During the treatment period, patients must actively cooperate with the doctor for treatment, follow the doctor’s instructions, reasonable use of medication, good postoperative care after surgery, regular medical review to avoid recurrence.