Bone is one of the most common metastatic sites of malignant tumors, and most of them are multiple bone metastases. Lung cancer can also metastasize to the bone, among which bone metastasis caused by adenocarcinoma of the lung is more common. Symptoms of bone metastasis Bone metastasis is usually asymptomatic in the early stage, but bone isotope scan can detect the lesioned bone. Bone metastasis symptoms are related to the location and quantity of tumor metastasis. For example, chest pain caused by rib metastasis of lung cancer is mostly manifested as pain confined to the chest wall area with clear pressure points. Spinal metastasis causes pain in the middle of the back or at the lesion site, while bone metastasis in the extremities or trunk causes limited pain in that area. Although bone metastasis is not directly life-threatening, it can cause serious consequences such as paralysis if the tumor metastasizes to weight-bearing bones such as cervical, thoracic and lumbar vertebrae. Therefore, patients with bone metastasis from lung cancer should be treated promptly. The main symptoms of bone metastases are gradually increasing local pain, pathological fracture, spinal cord and nerve compression, and even hypercalcemia in the late stage. The pain and other symptoms caused by bone metastases often become the greatest pain for tumor patients. Vertebral fractures can cause deformation of the spine, restriction of movement, and even lead to paralysis. The occurrence of bone complications can also have a serious psychological impact on patients, further severely reducing the quality of life of cancer patients. The treatment of tumor requires close collaboration of multiple programs, and the treatment of bone metastasis is an important part of comprehensive tumor treatment, so it is not possible to apply only one method, nor should we pay attention to bone metastasis and ignore the treatment of primary tumor and metastases from other sites. There are many methods to treat bone metastases, and it is more important that doctors should reasonably choose different treatment methods such as surgery, chemotherapy, radiotherapy, nuclear therapy, bisphosphonate drugs and pain medication according to the specific conditions of patients, so as to minimize the pain of patients and improve the quality of survival. Many people have many questions about how to treat bone metastasis and how to cure bone metastasis? For lung cancer, it is usually osteolytic bone metastases. The reduction of the destruction area of the lesion, the appearance of sclerotic edge or thickening of the sclerotic edge around the lesion, the reduction or decrease of the nuclein concentration area, and the decrease of the MRI T2-weighted image signal all indicate the effective treatment. Bone metastases from lung cancer are most likely to occur in the spine and proximal trunk bones, with 50% occurring in the spine, 25% in the femur, and 12% in the ribs and sternum. The most likely locations for bone metastasis are: hip bone, spine, chest rib, scapula, and leg joint in order. How to determine whether there are signs of bone metastasis? Usually, after the diagnosis of lung cancer, if there is soreness, pain or discomfort in these areas, or if there is a strange sound in the bones when walking, you should consider whether there is bone metastasis or not, and then you should go to the hospital for bone scan as soon as possible.