Pain on both sides of the buttocks may only be physiological phenomenon, does not mean that any disease, but also for pathological phenomena such as muscle strain or sciatic nodule cysts, sciatic nerve compression and so on. 1. Physiological: physiological situation, we carry out normal exercise labor, do exercise more strenuous or longer, will lead to pain on both sides of the buttocks, will also be accompanied by pain in other parts of the body, this situation belongs to the normal physiological phenomenon, and does not indicate any disease. 2. Pathology: Pathology is commonly associated with sciatic nerve compression or sciatic tubercle cysts, as well as aseptic inflammation of the muscle and soft tissues, which should be combined with one’s own exercise history or history of falls, to briefly determine whether the symptoms are caused by muscle or nerve contusion, and should be promptly sought medical attention. Pain on both sides of the buttocks may also be caused by herniated disc compression or spinal stenosis, etc., which should be promptly consulted for a clear diagnosis and treatment.