Scientific and effective nursing care can help to promote active treatment, eliminate fear, reduce pain and recover as soon as possible. For example, patients with long-term bed rest should turn their backs and change their lying position to prevent bedsores. For patients with bleeding, oral care should be done to keep the respiratory tract open and prevent asphyxia caused by vomiting and inhalation. Patients with severe cancer pain should be given timely and effective analgesic and other symptomatic treatments. Family members should also give patients spiritual comfort to eliminate patients’ fear, and at the same time closely observe patients’ vital signs to detect critical lesions and take effective treatment measures in time; 2. Psychological care: once patients are diagnosed with liver cancer, they will suffer a great blow to their spirits and eagerly expect malignant tumors to be negated, so their moods are complicated and agitated. In the late stage, they often show fear, anxiety and panic, and are often very sensitive to the language and attitude of medical workers because of high tension, and with the development of the disease, most of them lose confidence in treatment and even have the idea of early death for relief. At this stage, medical staff should be more careful and cautious in their speech, gentle and elegant demeanor, work in a steady and orderly manner, be able to detect the patient’s psychology, choose the appropriate language to comfort the patient, in order to reduce the patient’s psychological pain, so that the patient maintains an optimistic mental state,. Do the work of family members and cooperate with each other to give psychological support to patients, and try to meet the requirements of patients if possible; 3.Dietary care: patients with liver cancer have no systemic symptoms in the early stage, but in the late stage, they show cachexia, weakness, loss of appetite, anemia, fever and other cachectic symptoms, and are also prone to malnutrition, hypoproteinemia, low resistance and other complications. Therefore, patients with liver cancer should pay attention to daily dietary care to enhance resistance. The diet of patients with advanced liver cancer should be diversified and highly nutritious, and should be based on less and more meals, warm and soft, easy to digest and light diet.