Malignant pleural effusion (pleural fluid) is a common symptom of advanced stage lung cancer and malignant metastasis. The large amount of fluid in the pleural cavity not only compresses the lungs and causes chest tightness and discomfort, but also may cause severe respiratory difficulty, wheezing or co-infection, which is life-threatening. Therefore, malignant pleural effusion should be treated actively. There are two main methods of treatment, one is to extract the pleural fluid from the pleural cavity, and the other is to make the pleural adhesions between the dirty and wall layers occlude and no longer produce pleural fluid. In the past, most drugs were injected into the pleural cavity to make the adhesions between the dirty and wall layers of pleura, but the efficacy was poor; although thoracentesis can extract the fluid in the pleural cavity and relieve the symptoms of dyspnea, the pleural fluid can often appear again after the puncture, often requiring repeated punctures, increasing the patient’s pain and the chance of infection. So, what is a good treatment method for malignant pleural effusion (pleural fluid)? Minimally invasive surgery —- thoracoscopic surgical treatment has solved this problem. The current effective treatment method is: thoracoscopic talcum powder pleural fixation. By observing the TV screen connected to the thoracoscope, firstly, the pleural fluid is thoroughly aspirated and the adhesions on the lung surface are released, so that the lung is re-opened and the patient’s breathing is improved; then sterilized talcum powder is evenly sprayed into the thoracic cavity, so that adhesions and atresia occur in the dirty and wall layers of the pleura and no more pleural fluid is produced, thus effectively relieving the symptoms of advanced cancer patients, slowing down the deterioration process, improving the patient’s quality of life, and can win the patient the opportunity for further treatment.