1, gender: women are more likely to develop osteoporosis than men. 2.Race: The risk of osteoporosis varies among different racial groups. Caucasians are more likely to develop osteoporosis. 3, age: as age increases, the risk of osteoporosis increases. 4, Estrogen deficiency. 5, lighter weight people and people with low body mass index. 6, smokers. 7, drinking alcohol and caffeine. 8, people with a family history of osteoporosis. 9.History of fracture. 10.Delay in menarche. 11.Advancement of menstruation. 12.Low endogenous estrogen level.