The two leading causes of chronic kidney disease are diabetes and hypertensive disorders, which account for about two-thirds of all cases. When your blood sugar is too high, after a diagnosis of diabetes. Then it can damage many organs in your body, including your kidneys and heart, as well as your blood vessels, nerves and eyes. When you have high blood pressure, if left unchecked or poorly controlled, it can lead to heart disease, stroke and kidney disease. And chronic kidney disease can also cause high blood pressure. Other conditions that can affect the kidneys are: 1. Glomerulonephritis, a group of diseases that can cause inflammation and damage to the glomerulus. This is the third most common type of chronic kidney disease. 2. hereditary diseases, such as polycystic kidney, which can form many large cystic cavities in the kidney and damage the tissue around it. 3.Fetal malformations that arise when the fetus is developing in its mother’s body. For example, there may be ureteral stenosis that prevents the normal flow of urine, causing urine to reflux into the kidney, which can cause infection and damage to the kidney. 4.Systemic lupus erythematosus and other diseases that affect the human immune system. 5, obstruction caused by kidney stones, tumors or prostate enlargement in men. 6, repeated urinary tract infections, etc.