(Disclaimer: This article is only for scientific purposes, in order to protect the privacy of patients, the relevant information in the following content has been processed) Abstract: 69-year-old Auntie Zhang often appeared short of breath and chest tightness after activities in the past 10 years, which could be alleviated after resting, and last time she came to the hospital to take a blood gas analysis to check the chronic respiratory failure, and due to the mild symptoms, the symptoms disappeared due to the aminophylline tablets. 7 days ago, the sudden onset of breathlessness, which was aggravated by the activities, and poor mental state and general weakness. Poor mental status, generalized weakness, after blood gas analysis, pulmonary function tests, again admitted to the hospital with chronic respiratory failure, the symptoms disappeared after 2 weeks of medication, and no physical discomfort was seen after 1 month of discharge. Basic information] Female, 69 years old [Type of disease] Chronic respiratory failure [Hospital] The First Affiliated Hospital of China Medical University [Date of consultation] February 2020 [Treatment plan] Nebulized inhalation (ipratropium bromide aerosol, salmeterol ticlopidine powder inhalation) + intravenous injection (niclosamide injection) [Treatment cycle] Hospitalized with medication for 2 weeks, discontinued and discharged from the hospital after improvement of the symptoms, and was discharged for 1 month. Review 【Treatment effect】physical symptoms gradually disappeared and the condition was stabilized I. Initial Consultation 69-year-old Auntie Zhang came to our hospital complaining of chest tightness and shortness of breath every time after activity for 10 years, which could be alleviated after resting, and the last time she visited our hospital, she took a blood gas analysis and found that the partial pressure of carbon dioxide in the blood was 56mmHg, and the partial pressure of oxygen was 58mmHg, which diagnosed chronic respiratory failure. Aminophylline tablets were taken to dilate the bronchial tubes, and the symptoms disappeared. Seven days ago, she suddenly had unexplained breathlessness, which was worse after activity, and her mental state was poor, she felt a little weak, and after blood gas analysis, she found that her respiratory failure had worsened, and she found chronic obstructive pulmonary disease during pulmonary function test, considering chronic respiratory failure caused by chronic obstructive pulmonary disease, and she complained that she had a history of hypertension, and she could be considered to be transferred to another department for treatment of the disease after receiving treatment in our department. After the diagnosis was made clear, she was considered to be suffering from carbon dioxide retention and hypoxia, and was treated conservatively after consulting and communicating with her. Firstly, oxygen therapy was given to Auntie Zhang, wearing an oxygen mask to make her inhale more oxygen as soon as possible, and then the bronchodilator ipratropium bromide aerosol was taken to dilate the bronchial tubes, improve the symptoms of hypoxia, and increase the level of oxygen in the blood. At the same time, intramuscular injection of niclosamide injection was given to excite the respiratory center in order to increase airway ventilation and ventilation and improve carbon dioxide retention. As Auntie Zhang’s respiratory failure was caused by chronic inflammation in the airway that triggered the attack of chronic obstructive pulmonary disease, Salmeterol Ticarcoson Powder Inhaler was taken to dilate the bronchial tubes and inhibit the inflammation of the airway, and the spasm of the airway could be relieved after the inflammation improved, which was helpful in the treatment of the respiratory failure. Third, the treatment effect of oxygen inhalation and the use of ipratropium bromide aerosol, niclosamide injection, salmeterol ticarcoson powder inhaler for 2 weeks after the treatment, Auntie Zhang’s breathlessness, breathlessness after activity of the symptoms disappeared, the mental state returned to normal, the weakness of the whole body disappeared, suggesting that hypoxia as well as carbon dioxide retention disappeared, after the blood gas analysis found that significant abnormality of the respiratory failure plus was corrected, the cessation of the use of drugs and After blood gas analysis, the respiratory failure was corrected, the medication was stopped, and the patient was discharged from the hospital for recuperation. One month after stopping the medication, Auntie Zhang was found to be in good health. Auntie Zhang’s condition improved after receiving oxygen and medication, and I was glad to see her improvement. However, due to the history of COPD and structural changes in her lungs, she needed to be careful not to go to an environment with dirty air and low oxygen content after discharge from the hospital, as this would easily lead to a relapse of the respiratory failure after airway stimulation or oxygen deprivation. Usually also need to avoid strenuous exercise, this is because strenuous exercise will lead to an increase in body oxygen demand, but there are lung lesions in the population’s oxygen absorption capacity is relatively weakened, after strenuous exercise is prone to hypoxia. In life, we need to pay attention to eat more food rich in high quality protein, vitamins and other nutrients, such as chicken, beef, milk, as well as tomatoes, spinach, eggplants, etc., which can improve the quality of the body and help the body to recover. V. Personal Insights Auntie Zhang’s chronic respiratory failure was treated with medication, which showed significant improvement in physical symptoms and a better prognosis. After discharge from the hospital, if the typical chronic respiratory failure manifestations such as labored breathing, shallow and slow respiration, blood congestion of the skin, accelerated heartbeat, and elevated blood pressure are seen again, she should go to the hospital in time to actively take treatment measures. Avoiding prolonged hypoxia and carbon dioxide retention, which will affect the blood supply to the organs and metabolism of the whole body, and adversely affect the health of the body.