Hypertension is an important complication of gout, and about 50% of gout patients also suffer from hypertension. These two “bad friends” are working together to seriously endanger people’s health. The former Mr. Li has been taking antihypertensive drugs and uric acid detoxification drugs on time, but why did he develop kidney failure? It turns out that he ignored an important issue, the wrong choice of antihypertensive drugs! This problem is unknown to 80% of gout patients, and even doctors often ignore it when treating them. However, this is a very serious problem! Gout patients do not choose the right antihypertensive drugs, it is really “deadly”! The prevalence of hypertension among gout patients is about 50-60%, much higher than the prevalence of hypertension in the general population. Gout and high uric acid can lead to increased blood pressure, and high blood pressure aggravates gout and hyperuricemia. Gout patients need to be extremely careful when choosing antihypertensive drugs, otherwise it is easy to be counterproductive, aggravate gout, and even lead to deterioration of the disease! The simplest contraindication is: don’t use diuretics. 1, resolutely do not choose: we all know that eating more salt is prone to high blood pressure, because the intake of sodium is closely related to blood pressure, diuretics through the discharge of sodium diuretic to achieve the effect of lower blood pressure. Diuretic antihypertensive drugs are divided into three categories: strong diuretics (furosemide (tachyphylaxis)), medium-acting diuretics (such as thiazide diuretics, hydrochlorothiazide (dihydrochlorothiazide), chlorothiazide) and weak diuretics (such as spironolactone (Ativan), aminoglutethimide, amiloride, indapamide (Shoubisan) and various compound antihypertensive drugs), all three diuretic antihypertensive drugs may impede the excretion of uric acid, leading to an increase in uric acid. 2, as far as possible not to choose: B-blockers, such as propranolol class such as the heart, Metronapril class such as betaloc. 3, the second choice: angiotensin-converting enzyme inhibitor drugs, such as enalapril class esu, fosinopril class such as mono. 4.Preferred: Coxsartan class such as Coxsackie or amlodipine class such as Loxodil, both of which have the dual effect of lowering blood pressure and lowering uric acid.