High HCG can be broadly classified into two possibilities: physiologic and pathologic elevations. HCG, or human chorionic gonadotropin, is physiologically elevated, mostly in pregnant women. This is a physiological increase and is normal for women of childbearing age who are normally pregnant. The HCG value is usually measured in the serum and urine of pregnant women on the 7th day after fertilization, and this test can be used as a diagnostic basis for normal pregnancy. The serum HCG concentration can reach a peak in the 8th-10th week of pregnancy and continues to decline rapidly after 10 days, but is still higher than normal until 1-2 weeks after delivery. In addition, some diseases can also lead to elevated HCG, such as ectopic pregnancy, ovarian germ cell tumors, trophoblastic cell tumors (including staphyloma and chorioepithelial carcinoma), seminoma, embryonal cell tumors, testicular cancer, cervical cancer, and breast cancer can all show pathological elevation. Therefore, when the test result indicates a high HCG value, women of childbearing age should first consider pregnancy, and the diagnosis can be clarified by ultrasound and other auxiliary examinations, and further exclude the presence of other pathological factors.