1.What tests are needed before implementing assisted reproductive technology
(1) The female side must check: sex hormone six items, blood routine + blood type two items, liver and kidney function, coagulation function, teratogenic eight items, hepatitis B and half + hepatitis C + HIV + syphilis, anti-sperm antibodies, anti-cardiolipin antibodies, urine routine, cervical cell smear, white belt routine + chlamydia + gonococcus, gynecological ultrasound examination, electrocardiogram, chest X-ray;
(2) Optional tests for the female partner: chromosomes, post-coital test, antibody, and gene test for geodystrophy;
(3) Male partner must check: semen routine + morphological analysis + sperm tail hypotonic swelling test + eosin staining + sperm membrane antibody, blood routine + blood type two, blood anti-sperm antibody, hepatitis B and half + hepatitis C + HIV + syphilis, semen mycoplasma + chlamydia + gonococcus, semen leukocyte peroxidase staining examination;
(4) The male partner’s optional tests: chromosome + Y chromosome microdeletion, sex hormone, testicular biopsy, testicular ultrasound, sperm acrosome reaction, prostate fluid routine, urine routine.
2.Doing artificial assisted technology requires those documents
According to the relevant policies of the Ministry of Health, couples who undergo assisted reproductive technology must provide the hospital with their ID cards, marriage certificates, family planning certificates (family planning service certificates, second birth certificates, birth certificates issued by family planning offices at the town level or above), or if the couple is a foreigner (including Hong Kong, Macau and Taiwan), only the marriage certificate, ID cards or passports of both parties. All documents need to be photocopied for record;
The family planning certificate is valid for one year, if your certificate has expired, please go to the relevant department for annual review.
3.What is Intra-Uterine Insemination (IUI)
The semen of the husband is injected into the uterine cavity after washing and screening for optimization during ovulation of the woman. It is suitable for patients with husband’s impotence, premature ejaculation, lack of cervical mucus during female’s ovulation and other cervical factors of infertility, partial immune infertility, slight oligospermia and weak sperm of male partner, etc.
4.What is called conventional IVF (IVF-ET)
IVF-ET is the abbreviation of in vitro fertilization-embryo transfer, which is the process of removing eggs and sperm from infertile couples, fertilizing them in vitro, culturing them into embryos and then transferring them into the patient’s uterine cavity for implantation to achieve pregnancy, commonly known as IVF.
5. What are the conditions suitable for IVF?
(1) Congenital tubal occlusion or abnormal development, such as atresia of the umbilical end into a blind end;
(2) Those with damaged or blocked fallopian tubes (e.g. after pelvic inflammatory disease), who have lost the function of egg collection and whose treatment is ineffective;
(3) infertile patients who have had their fallopian tubes removed after ectopic pregnancy or whose tubes are blocked or functionally damaged despite conservative treatment
(4) patients with endometriosis who are unable to conceive despite surgical and pharmacological treatment;
(5) patients who have requested to have children again after tubal ligation, or who are unable to have children despite microanastomosis;
(6) Those who have been married for many years and have failed to conceive through artificial insemination for unknown reasons and are too old;
(7) Those who have low sperm count or poor vitality;
(8) Azoospermia on routine semen examination, but mature spermatozoa can be seen on testicular biopsy;
(9) Those with hereditary diseases such as hemophilia, pseudohypertrophic muscular dystrophy, chromosomal abnormalities such as congenital dysmorphism, monogenic diseases such as sickle cell anemia, thalassemia, etc.
6.Determine how long it takes to do IVF treatment
The whole process takes about 2-3 menstrual cycles. The normal pre-IVF examination is 2 weeks, blood will be drawn on the 2nd-4th day of menstruation, chlamydia and cervical smear will be performed after the menstruation is clean, and all the information and “three certificates” will be brought to build the medical record. On the 20th-23rd day of menstruation, we will start IVF-ET treatment with the application of GnRHa (down regulation injection), 1 week after down regulation, we will check the ultrasound to see if there are any cysts, 14-18 days after down regulation, we will start to monitor the follicles with ultrasound, the routine ovulation time is about 9-12 days, when the follicles are big enough, we will inject HCG (around 9 pm), 35-36 hours after HCG injection, the female partner will collect the eggs and the male partner will collect the sperm. The female partner will retrieve the eggs and the male partner will retrieve the sperm and return to the hospital 3 or 5 days later for embryo transfer.