The main clinical signs and symptoms of osteoporosis are: generalized pain, shortening of height, hunchback, fragility fracture and limitation of breathing. Generalized pain is the most common and main symptom of osteoporosis. The cause is mainly due to high bone turnover and increased bone resorption. In the process of bone resorption, the destruction and loss of bone trabeculae and the destruction of subperiosteal cortical bone can cause generalized bone pain, with low back pain being the most common. Another important cause of pain is fracture, i.e. low back pain caused by compression fracture of the spine by external pressure or non-external pressure, flattened vertebrae, cuneiform vertebrae and fish-like deformation. It was found that the highest incidence of vertebral fractures was found in the thoracic 12 to lumbar 1 (T12-L1) vertebrae, due to the loss of lateral support of the rib ring in this segment, resulting in a sudden increase in weight bearing; at the same time, the thoracic vertebrae above T12-L1 are supported by the rib ring, resulting in an increase in the relative mobility of the vertebral body when the stress is transmitted to this region, resulting in a significantly higher incidence of fractures in this segment. Compression fracture pain is characterized by fasciculation-like and electric shock-like pain, which increases significantly with activity and turning.