Gallstones may require surgical treatment even if there are no painful symptoms. In general, if gallstones are not painful, patients can be treated without surgery and can be observed with regular follow-up. However, due to individual differences, there may be deviations, and some patients may need surgery even if they are not in pain. The need for surgery usually depends on the specific test results.1. Stone condition: For patients with more and larger stones, i.e. stones more than 2-3 cm in diameter and the number of stones is greater than 3, surgery is usually recommended. Multiple and large stones are easy to stimulate the gallbladder wall and secondary infection, which in the long run has the possibility of significantly increasing the probability of chronic inflammation of gallbladder and gallbladder cancer; 2. Gallbladder function loss: If combined with calcification of gallbladder wall, porcelain gallbladder, serious atrophy of gallbladder and serious function loss, this may increase the risk and probability of gallbladder cancer. Especially in the case of long-term stimulation by stones, gallbladder cancer is more likely to occur, and gallbladder cancer is more malignant, so surgery is recommended. In addition, if the gallbladder is filled with stones, the gallbladder is filled with the whole gallbladder and loses its original function of storing and concentrating bile, so surgery is also needed; 3. Thickening of gallbladder wall: if the gallbladder wall is significantly thickened, it means that the inflammation of gallbladder is more serious and the risk and probability of gallbladder cancer increases, so surgery is recommended; 4. Combined gallbladder polyps: if the combined gallbladder polyps exceed 1cm, surgery is considered. As polyps combined with stones are easy to stimulate each other, especially the stones repeatedly stimulate the polyps and make their enlargement more obvious; 5. Others: If the patient is an elderly person with underlying diseases such as combined diabetes, hypertension and heart disease, even if there are no symptoms, surgery is recommended to remove the gallbladder if the underlying diseases are well controlled.