Sclerofibromatosis, also known as aggressive fibromatosis and ligamentous fibromatosis, is a rare disease that statistically can occur in 2-4 new cases per year in a population of one million. The occurrence of these 2-4 new cases may be related to the following factors: 1. Trauma: In clinical practice, it can be seen that some patients with hard fibromas have a history of trauma at the site of onset before the onset of the disease. Li Shu, Department of Bone and Soft Tissue Oncology, Peking University Cancer Hospital, Beijing, China 2. Elevated estrogen level: Sclerofibroma tends to occur in women. After menopause, when estrogen decreases significantly, the hard fibroids on the body can naturally subside, suggesting that the occurrence of hard fibroids may be related to elevated estrogen level. 3, familial adenomatous polyposis: It has been reported in the literature that patients with familial adenomatous polyposis have a higher chance of developing hard fibroids than ordinary people. This is because the APC gene, the causative gene for familial adenomatous polyposis, is associated with the causative gene for hard fibroids. A hard fibroid is a slow-growing tumor that is hard to the touch but rarely hurts. And when the patient is left untreated or improperly treated, the tumor grows larger and larger, which in turn invades other normal tissues and causes effects. As for what harm hard fibroids can cause to patients, it is mainly related to the location where the tumor grows. Again, it should be clear that sclerofibroma is a benign tumor and is not fatal in itself. However, if the tumor grows in the pelvic or abdominal cavity, when the mass is very large, it may be life-threatening by compressing the surrounding organs. For example, it may compress the adjacent ureter, which may lead to ureteral obstruction and even kidney failure in serious cases; or compression of intestinal canal may cause intestinal obstruction and other diseases. It has been observed that a higher percentage of pediatric patients have tumors in the hip, and these sclerofibromas can cause limited hip movement. For children who are growing, prolonged compression of one lower extremity may affect their normal development, resulting in bilateral lower extremity inequality, i.e., one leg is long and the other is short. In a word, where the tumor grows up and presses on, where will be “bad luck”. So, how to detect this “troublemaker” in early stage? Because hard fibroid is a soft tissue tumor, MRI can see the soft tissue more clearly than CT and B-ultrasonic examination. However, the final “interpretation” of the tumor still lies in the pathological diagnosis, especially for first-time patients, who must obtain pathological results before surgery. In addition, because hard fibroids are rare and relatively complicated to diagnose, many physicians lack knowledge of the disease, and it is difficult for some physicians to think of a lump on a patient’s body as a hard fibroid. Therefore, if a patient finds a lump on the body that is relatively hard and cannot be pushed, it is recommended to see a specialist at a specialized hospital.